Self-organisation of planar and tripod-shaped DNA stars confined to the water–air interface

Author(s)
Clemens Jochum, Nataša Adžić, Emmanuel Stiakakis, Gerhard Kahl, Christos N. Likos
Abstract

Using molecular dynamic simulations of coarse-grained models, we study the self-organisation of star-shaped all-DNA constructs, composed of suitably intertwined single-stranded DNA chains, confined to water-air interface. Two configurations of DNA stars are considered: planar and tripod with respect to whether the entire star is fixed to an interface or only its terminating nucleotides, while the rest is allowed to dive into a water where high concentration of monovalent salt is dissolved. Calculated structural properties of the solutions they form as well as their dynamical features, investigated in a range from low- to intermediate densities, reveal that both systems stay in liquid state maintaining remarkably similar properties despite striking differences in the conformation of the composing molecules.

Organisation(s)
Computational and Soft Matter Physics
External organisation(s)
Technische Universität Wien, University of Belgrade, Forschungszentrum Jülich
Journal
Molecular Physics
No. of pages
16
ISSN
0026-8976
DOI
https://doi.org/10.1080/00268976.2025.2472020
Publication date
03-2025
Peer reviewed
Yes
Austrian Fields of Science 2012
103043 Computational physics, 103015 Condensed matter
Keywords
Portal url
https://ucrisportal.univie.ac.at/en/publications/9b35e840-53a3-4520-8b45-e17ab9a3937c